The two Timberwolves, who were instrumental in last season's Knicks success, return to the Garden Friday night, but DiVincenzo is out with a toe sprain.

Karl-Anthony Towns likely is the player the Knicks can least do without, especially with Mitchell Robinson still unable to practice.

It’ll represent the durable DiVincenzo’s first DNP of the season for the T’wolves and puts a damper on an anticipated matchup between offseason trade partners.

It sucks,” Randle said. “I guess we’ll never know what could’ve been. I think the more unfortunate part is everything was a build, a constant build — I feel like all our teams overachieved year

There was no Villanova reunion. There was no anticipated spat with Rick Brunson to keep an eye on. Former fans didn’t have the chance to watch him play on the Garden floor during what has been a hot streak for the Delaware native.

DiVincenzo was recently promoted to the starting lineup over Mike Conley and was averaging 17.5 points and 4.7 assists as a starter. Minnesota was 4-2 in those games.

Friday night marked Randle’s first game back at Madison Square Garden since the Knicks traded him and Donte DiVincenzo to the Minnesota Timberwolves in the three-team blockbuster that brought center Karl-Anthony Towns to New York.

The Knicks' Karl-Anthony Towns (thumb) is questionable for Friday's game against the Timberwolves, who will be without starter Donte DiVincenzo (toe).

DiVincenzo was recently promoted to the starting lineup over Mike Conley and was averaging 17.5 points and 4.7 assists as a starter. Minnesota was 4-2 in those games.

Donte DiVincenzo is out indefinitely due to a left toe injury, the Minnesota Timberwolves announced on Monday.

Randle played a secondary role in the Timberwolves’ 116-99 win, taking a backseat in the spotlight as Anthony Edwards dazzled with 36 points, 13 rebounds and seven assists.